The need for a refined understanding of CYP2D6 in second-generation antipsychotic outcomes in children and adolescents-Reference-Cited by-同舟云学术

The need for a refined understanding of CYP2D6 in second-generation antipsychotic outcomes in children and adolescents

Published:2021-06 Issue:8 Volume:22 Page:447-450
ISSN:1462-2416
Container-title:Pharmacogenomics
language:en
Short-container-title:Pharmacogenomics

Author:

Rossow Katelyn M¹^ORCID,Vaughn Samuel E²,Strawn Jeffrey R³⁴^ORCID,Van Driest Sara L¹⁵^ORCID,Ramsey Laura B⁴⁶^ORCID

Affiliation:

1. Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA

2. Department of Pediatrics, Division of Child & Adolescent Psychiatry, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA

3. Department of Psychiatry & Behavioral Neuroscience, College of Medicine, University of Cincinnati, Cincinnati, OH 45219, USA

4. Department of Pediatrics, Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45219, USA

5. Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA

6. Department of Pediatrics, Division of Research in Patient Services, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA

Abstract

Tweetable abstract High-quality studies examining the influence of CYP2D6 on the exposure and tolerability of antipsychotics in youth are needed to mitigate the limitations of prior studies.

Funder

Eunice Kennedy Shriver National Institute of Child Health and Human Development

National Institute of General Medical Sciences

Publisher

Future Medicine Ltd

Subject

Pharmacology,Genetics,Molecular Medicine

Link

https://www.futuremedicine.com/doi/pdf/10.2217/pgs-2021-0049

Reference18 articles.

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2. Antipsychotic Medication Prescribing Trends in Children and Adolescents

3. CDER FDA. Highlights of prescribing information Risperdal® (risperidone) tablets, RISPERDAL® (risperidone) oral solution, RISPERDAL® M-TAB® (risperidone) orally disintegrating tablets. (2009).

4. Association of Antipsychotic Treatment With Risk of Unexpected Death Among Children and Youths

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