Real-world treatment patterns and stroke risks among patients with atrial fibrillation in China

Author:

Wang Rosa1ORCID,Ning Ning2,Wang Shaoping3,Ye Xin1,Hu Xiaohan4,Xuan Jianwei4

Affiliation:

1. Daiichi Sankyo Inc, 211 Mt Airy Rd, Basking Ridge, NJ 07920, USA

2. University of Southern California, 635 Downey Way, Verna & Peter Dauterive Hall (VPD), Los Angeles, CA 90089, USA

3. Beijing Anzhen Hospital, No. 2 Anzhen Rd, District, Beijing, 100029, China

4. Health Economic Research Institute, Sun Yat-Sen University, 135 Xingang W Rd, Binjiang Road, Haizhu District, Guangzhou, Guangdong Province, 510275, China

Abstract

Aim: To describe patient characteristics, treatment patterns and stroke risks for patients with newly diagnosed atrial fibrillation (AF) in China. Patients & methods: Patients with AF were identified from an electronic medical record database in China (n = 22,535). Results: Less than half of patients (n = 9971; 44.2%) received antithrombotic medications following AF diagnosis; of these patients, 93.7% received anticoagulants and 71.3% received antiplatelets. Only 27.6% of patients received oral anticoagulants. Multivariate Cox proportional hazard model analysis found that patients treated with antithrombotic medications had a significantly lower risk of stroke compared with patients who were not treated (hazard ratio: 0.4; 95% CI: 0.37–0.43). Conclusion: The results suggest that antithrombotic medications, especially oral anticoagulants, are underused in China.

Funder

Daiichi Sankyo, Inc

Publisher

Future Medicine Ltd

Subject

Cardiology and Cardiovascular Medicine,Molecular Medicine

Reference29 articles.

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