Factors influencing mothers’ decision to enroll their HIV-negative children in a hypothetical HIV vaccine trial

Author:

Williamson Victoria1,Coetzee Bronwyne2,Kagee Ashraf2,Tomlinson Mark2

Affiliation:

1. Department of Psychology, University of Bath – Claverton Down, Bath, Bath BA2 7AY, UK

2. Department of Psychology, Stellenbosch University – RW Wilcocks Building, Ryneveld Street, Stellenbosch 7600, South Africa

Abstract

Despite advances in preventive treatments for HIV, children continue to become infected with HIV. Research has investigated adult and adolescents’ willingness to participate in hypothetical HIV vaccine trials; however, maternal willingness to enroll their infants in such trials remains underexplored. Aim: This study explored the factors influencing mothers’ decision-making about enrolling their HIV negative infants in a hypothetical HIV vaccine trial. Methods: HIV infected and uninfected mothers (n = 22) were interviewed. Results: Several factors were identified as influencing the mothers’ decisions, including perceptions and knowledge of HIV and vaccines. Conclusion: Maternal concerns about protecting their infants from HIV were also identified and mothers indicated that they were eager to vaccinate their children. Insufficient information and reassurance regarding vaccine trial safety and efficacy influenced maternal reluctance to enroll their child.

Publisher

Future Medicine Ltd

Subject

Virology

Reference38 articles.

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Acceptability of a future HIV vaccine: A rapid scoping review;JAIDS Journal of Acquired Immune Deficiency Syndromes;2024-05-21

2. Welcome to the 13th volume of Future Virology;Future Virology;2018-01

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