Why should we target viral serine proteases when developing antiviral agents?-Reference-Cited by-同舟云学术

Why should we target viral serine proteases when developing antiviral agents?

Published:2016-12 Issue:12 Volume:11 Page:745-748
ISSN:1746-0794
Container-title:Future Virology
language:en
Short-container-title:Future Virology

Author:

Skoreński Marcin¹,Grzywa Renata¹,Sieńczyk Marcin¹

Affiliation:

1. Faculty of Chemistry, Division of Medicinal Chemistry & Microbiology, Wroclaw University of Science & Technology, Wybrzeze Wyspianskiego 27, 50–370 Wroclaw, Poland

Publisher

Future Medicine Ltd

Subject

Virology

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fvl-2016-0106

Reference20 articles.

1. Approved Antiviral Drugs over the Past 50 Years

2. Viral Proteases as Targets for Drug Design

3. Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide

4. An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

5. Treatment of HCV infection with the novel NS3/4A protease inhibitors

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3. Racemization Hypothesis of COVID-19. Tip of the Iceberg;Journal of Psychology and Neuroscience;2020-08-04

4. Binding recognition of substrates in NS2B/NS3 serine protease of Zika virus revealed by molecular dynamics simulations;Journal of Molecular Graphics and Modelling;2019-11

5. Quantum Mechanics/Molecular Mechanics (QM/MM) Calculations Support a Concerted Reaction Mechanism for the Zika Virus NS2B/NS3 Serine Protease with Its Substrate;The Journal of Physical Chemistry B;2019-03-07