Prevalence and phylogenic study of human T-lymphotropic virus 1 in patients with thalassemia in the northeast of Iran-Reference-Cited by-同舟云学术

Prevalence and phylogenic study of human T-lymphotropic virus 1 in patients with thalassemia in the northeast of Iran

Published:2017-05 Issue:5 Volume:12 Page:253-258
ISSN:1746-0794
Container-title:Future Virology
language:en
Short-container-title:Future Virology

Author:

Abedi Farshid¹²,Mozhgani Sayed-Hamidreza³,Rahimzadegan Marzieh²,Gudarzi Hoda³,Valizadeh Narges⁴,Rezaee Seyed Abdolrahim⁴

Affiliation:

1. Department of Infectious Disease, Birjand University of Medical Sciences, Birjand, Iran

2. Department of Infectious Disease, Mashhad University of Medical Sciences, Mashhad, Iran

3. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

4. Immunology Research Center, Inflammation & Inflammatory Diseases Division, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract

Aim: This study aimed to investigate the frequency and phylogenetic distribution of human T-lymphotropic virus type 1 (HTLV-1) in thalassemia cases. Methods: Between 2006 and 2013, a total of 100 thalassemic individuals were investigated for HTLV-1 infections. Results: Four people (4%) were reactive for HTLV antibodies. No considerable correlation was seen between factors such as age, blood transfusion history, surgery, marital status, gender and blood types. All HTLV-1 sequences belonged to the transcontinental (A) subgroup in the cosmopolitan (a) subtype. Conclusion: In addition to phylogenetic distribution, our results demonstrate that the prevalence of HTLV-1 infection among thalassemia patients in Mashhad is higher than that of previous studies.

Publisher

Future Medicine Ltd

Subject

Virology

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fvl-2016-0107

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