Lymph node ratio has prognostic value related to the number of positive lymph nodes in patients with vulvar cancer-Reference-Cited by-同舟云学术

Lymph node ratio has prognostic value related to the number of positive lymph nodes in patients with vulvar cancer

Published:2018-10 Issue:23 Volume:14 Page:2343-2351
ISSN:1479-6694
Container-title:Future Oncology
language:en
Short-container-title:Future Oncology

Author:

Wu San-Gang¹,Zhang Wen-Wen²,Li Feng-Yan²,Sun Jia-Yuan²,Zhou Juan³,He Zhen-Yu²

Affiliation:

1. Department of Radiation Oncology, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Xiamen 361003, PR China

2. Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou 510060, PR China

3. Department of Obstetrics & Gynecology, The First Affiliated Hospital of Xiamen University, Xiamen 361003, PR China

Abstract

Aim: We investigated the value of the number of positive lymph nodes (PLNs) and lymph node ratio (LNR) on survival of vulvar cancer patients. Methods: A total of 2332 patients with vulvar squamous cell carcinoma were included from the SEER program. Results: In multivariate analysis, the number of PLNs and LNR were independent prognostic indictors of survival outcomes, a higher number of PLNs and a higher LNR had poorer survival outcomes. An LNR >0.2 was associated with poor survival outcomes according to the number of PLNs. Conclusion: The LNR has prognostic value related to the number of PLNs and may allow a more accurate determination of the lymph node status of vulvar cancer patients.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fon-2018-0279

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