Diagnostic and prognostic significance of serum CD26 level in Asian women with high-grade serous ovarian carcinoma-Reference-Cited by-同舟云学术

Diagnostic and prognostic significance of serum CD26 level in Asian women with high-grade serous ovarian carcinoma

Published:2019-06 Issue:16 Volume:15 Page:1863-1871
ISSN:1479-6694
Container-title:Future Oncology
language:en
Short-container-title:Future Oncology

Author:

Shao Shiqing¹,Wang Chen¹,Tian Jun¹,Zhang Hongxia¹,Wang Shelian¹,Du Yaowu²

Affiliation:

1. Department of Obstetrics & Gynecology, Huaihe Hospital, Henan University, Kaifeng, 475000, Henan Province, PR China

2. Laboratory for Nanomedicine, School of Basic Medical Science, Henan University, Kaifeng, 475004, Henan Province, PR China

Abstract

Aim: The aim of this study was to reveal the diagnostic and prognostic significance of serum CD26 level in high-grade serous ovarian carcinoma women in China. Methods: There were 229 high-grade serous ovarian carcinoma women and 365 controls. Baseline serum CD26 level was measured using ELISA. A 36-month post-operation follow-up was performed. Results: Baseline serum CD26 level ≤601.5 pg/ml was associated with the increased risk of ovarian carcinoma (OR: 1.67; 95% CI: 1.20–2.32). Baseline serum level of CD26 ≤589.7 pg/ml was related to the elevated risk of cancer death (HR: 1.33; 95% CI: 1.04–1.69). Conclusion: Baseline serum CD26 level might be an independent diagnostic and prognostic marker for high-grade serous ovarian carcinoma.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fon-2018-0725

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