Primary brain tumor patients admitted to a US intensive care unit: a descriptive analysis

Author:

Kang Jennifer H1ORCID,Swisher Christa B2,Buckley Evan D3,Herndon James E3,Lipp Eric S4,Kirkpatrick John P5,Desjardins Annick14,Friedman Henry S4,Johnson Margaret O14ORCID,Randazzo Dina M14,Ashley David M46,Peters Katherine B14ORCID

Affiliation:

1. Department of Neurology, Duke University Medical Center, Durham, NC 27710, USA

2. Department of Neurology, Atrium Health, Charlotte, NC 28203, USA

3. Department of Biostatistics & Bioinformatics, Duke University Medical Center, Durham, NC 27710, USA

4. Department of Neurosurgery, Duke University Medical Center, Durham, NC 27710, USA

5. Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA

6. Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA

Abstract

Purpose: To describe our population of primary brain tumor (PBT) patients, a subgroup of cancer patients whose intensive care unit (ICU) outcomes are understudied. Methods: Retrospective analysis of PBT patients admitted to an ICU between 2013 to 2018 for an unplanned need. Using descriptive analyses, we characterized our population and their outcomes. Results: Fifty-nine PBT patients were analyzed. ICU mortality was 19% (11/59). The most common indication for admission was seizures (n = 16, 27%). Conclusion: Our ICU mortality of PBT patients was comparable to other solid tumor patients and the general ICU population and better than patients with hematological malignancies. Further study of a larger population would inform guidelines for triaging PBT patients who would most benefit from ICU-level care.

Publisher

Future Medicine Ltd

Subject

General Medicine

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