Intracellular delivery of proteins by nanocarriers-Reference-Cited by-同舟云学术

Intracellular delivery of proteins by nanocarriers

Published:2017-04 Issue:8 Volume:12 Page:941-952
ISSN:1743-5889
Container-title:Nanomedicine
language:en
Short-container-title:Nanomedicine

Author:

Ray Moumita¹,Lee Yi-Wei¹,Scaletti Federica¹,Yu Ruijin¹²,Rotello Vincent M¹

Affiliation:

1. Department of Chemistry, University of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA 01003, USA

2. College of Chemistry & Pharmacy, Northwest A&F University, Yangling, Shaanxi 712100, PR China

Abstract

Intracellular delivery of proteins is potentially a game-changing approach for therapeutics. However, for most applications, the protein needs to access the cytosol to be effective. A wide variety of strategies have been developed for protein delivery, however access of delivered protein to the cytosol without acute cytotoxicity remains a critical issue. In this review we discuss recent trends in protein delivery using nanocarriers, focusing on the ability of these strategies to deliver protein into the cytosol.

Publisher

Future Medicine Ltd

Subject

Development,General Materials Science,Biomedical Engineering,Medicine (miscellaneous),Bioengineering

Link

https://www.futuremedicine.com/doi/pdf/10.2217/nnm-2016-0393

Reference62 articles.

1. Protein therapeutics: a summary and pharmacological classification

2. Biopharmaceutical benchmarks 2010

3. Tailoring nanocarriers for intracellular protein delivery

4. Gene therapy for cancer: present status and future perspective

5. Promises and Pitfalls of Intracellular Delivery of Proteins

Cited by 81 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. ECRG2/SPINK7 Tumor Suppressor as Modulator of DNA Damage Response;International Journal of Molecular Sciences;2024-05-28

2. Enhancing Cellular Uptake of Native Proteins through Bio-Orthogonal Conjugation with Chemically Synthesized Cell-Penetrating Peptides;Pharmaceutics;2024-05-03

3. Intracellular protein delivery: New insights into the therapeutic applications and emerging technologies;Biochimie;2023-10

4. Intracellular delivery of therapeutic proteins. New advancements and future directions;Frontiers in Bioengineering and Biotechnology;2023-05-25

5. Polymeric Micellar Systems—A Special Emphasis on “Smart” Drug Delivery;Pharmaceutics;2023-03-17