The role of p53 mutations as a prognostic factor and therapeutic target in inflammatory breast cancer-Reference-Cited by-同舟云学术

The role of p53 mutations as a prognostic factor and therapeutic target in inflammatory breast cancer

Published:2006-04 Issue:2 Volume:2 Page:247-255
ISSN:1479-6694
Container-title:Future Oncology
language:en
Short-container-title:Future Oncology

Author:

Yang Charles H¹,Cristofanilli Massimo

Affiliation:

1. Breast Medical Oncology, University of Texas – MD Anderson Cancer Center, Department of Breast Medical Oncology, Unit 1354, 1515 Holcombe Boulevard, Houston, TX 77030, USA

Abstract

Inflammatory breast cancer is a rare but lethal form of locally advanced breast cancer. Despite improvements in survival with the advent of multidisciplinary treatment regimens, 5-year survival rates remain disappointing, at approximately 30%. Numerous molecular markers have been investigated for their potential as useful prognostic and predictive markers of treatment response that would impact on the management of inflammatory breast cancer. This review discusses the current status of p53 mutations both as a prognostic marker and as a potential target for directed therapies.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

Link

https://www.futuremedicine.com/doi/pdf/10.2217/14796694.2.2.247

Reference80 articles.

1. Inflammatory breast cancer: a review.

2. Long-Term Follow-Up for Locally Advanced and Inflammatory Breast Cancer Patients Treated With Multimodality Therapy

3. Predictors of long-term outcome following high-dose chemotherapy in high-risk primary breast cancer

4. Molecular markers in breast cancer: Can we use c-erbB-2, p53, bcl-2 and bax gene expression as prognostic factors?

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Flexible Cationic Nanoparticles with Photosensitizer Cores for Multifunctional Biomedical Applications;Small;2018-05

2. Molecules That Drive the Invasion and Metastasis of Inflammatory Breast Cancer;Inflammatory Breast Cancer: An Update;2012

3. Analysis of Matrix Metalloproteinase-1 Gene Polymorphisms and Expression in Benign and Malignant Breast Tumors;Cancer Investigation;2011-10-19

4. Inflammatory Breast Cancer: Novel Preoperative Therapies;Clinical Breast Cancer;2010-02

5. Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells Mediate Metastasis and Poor Clinical Outcome in Inflammatory Breast Cancer;Clinical Cancer Research;2009-12-22