Nano-carriers of COVID-19 vaccines: the main pillars of efficacy-Reference-Cited by-同舟云学术

Nano-carriers of COVID-19 vaccines: the main pillars of efficacy

Published:2021-11 Issue:26 Volume:16 Page:2377-2387
ISSN:1743-5889
Container-title:Nanomedicine
language:en
Short-container-title:Nanomedicine

Author:

Constantin Carolina¹²^ORCID,Pisani Anissa³⁴^ORCID,Bardi Giuseppe³^ORCID,Neagu Monica¹²⁵^ORCID

Affiliation:

1. “Victor Babeş” National Institute of Pathology, 99-101 Spl Independentei, Bucharest, 050096, Romania

2. Colentina Clinical Hospital, 19-21, Sos. Stefan cel Mare, Bucharest, Romania

3. Nanobiointeractions & Nanodiagnostics, Istituto Italiano di Tecnologia, Via Morego 30, Genova, 16163, Italy

4. Department of Chemistry & Industrial Chemistry, University of Genova, Via Dodecaneso 31, Genova, 16146, Italy

5. University of Bucharest, 93–95 Spl Independentei, Bucharest, Romania

Abstract

As the current COVID-19 pandemic illustrates, vaccination is the most powerful method of disease prevention and public confidence in vaccines depends on their safety and efficacy. The information gathered in the current pandemic is growing at an accelerated pace. Both the key vital protein DNA/RNA messengers and the delivery carriers are the elements of a puzzle including their interactions with the immune system to suppress SARS-CoV-2 infection. A new nano-era is beginning in the vaccine development field and an array of side applications for diagnostic and antiviral tools will likely emerge. This review focuses on the evolution of vaccine carriers up to COVID-19-aimed nanoparticles and the immune-related adverse effects imposed by these nanocarriers.

Funder

Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii

NASR

Publisher

Future Medicine Ltd

Subject

Development,General Materials Science,Biomedical Engineering,Medicine (miscellaneous),Bioengineering

Link

https://www.futuremedicine.com/doi/pdf/10.2217/nnm-2021-0250

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