Psychometric validation of the Brain Symptom and Impact Questionnaire (BASIQ) version 1.0 to assess quality of life in patients with brain metastases

Author:

Thavarajah Nemica1,Ray Saurabh2,Bedard Gillian1,Zhang Liying1,Cella David3,Wong Erin1,Danjoux Cyril1,Tsao May1,Barnes Elizabeth1,Sahgal Arjun1,Soliman Hany1,Pulenzas Natalie1,Lechner Breanne1,Chow Edward1

Affiliation:

1. Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON, M4N3M5 Canada

2. Oncology AbbVie, Abbott Park, IL, USA

3. Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

Abstract

SUMMARY  Objective: To test the reliability, clinical and psychometric validity of the Brain Symptom and Impact Questionnaire (BASIQ) in patients with brain metastases. Methods: Brain metastases patients were interviewed using the BASIQ, Functional Assessment of Cancer-Brain (FACT-Br) and FACT-General (FACT-G) at baseline, with a follow-up assessment at 1 month. Results: Forty patients had complete one data and the median age was 64 years. Patients with higher KPS, ECOG of 2, primary breast cancer, or >3 brain metastases, scored higher on the symptom scale of the BASIQ. All subscales showed no significant change in patient symptoms from baseline to follow-up. Conclusion: This study supports that the reliability, clinical and psychometric validity of BASIQ to be used in brain metastases patients.

Publisher

Future Medicine Ltd

Subject

General Medicine

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