Diagnostic value of nucleic acid amplification tests for tuberculous pleural effusion-Reference-Cited by-同舟云学术

Diagnostic value of nucleic acid amplification tests for tuberculous pleural effusion

Published:2023-09 Issue:14 Volume:18 Page:971-983
ISSN:1746-0913
Container-title:Future Microbiology
language:en
Short-container-title:Future Microbiology

Author:

Wen Xu-Hui¹²,Han Yu-Ling¹²,Cao Xi-Shan¹,Zhao Wen¹,Yan Zhi¹²,Yan Li³,Wen Jian-Xun⁴,Hu Zhi-De¹^ORCID,Zheng Wen-Qi¹²^ORCID

Affiliation:

1. Department of Laboratory Medicine, the Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010010, China

2. Department of Parasitology, Basic Medical Sciences College of Inner Mongolia Medical University, Hohhot, 010050, China

3. Department of Respiratory & Critical Care Medicine, the Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010010, China

4. Department of Medical Experiment Center, Basic Medical Sciences College of Inner Mongolia Medical University, Hohhot, 010050, China

Abstract

Diagnosing tuberculous pleural effusion (TPE) is challenging for pulmonologists and laboratory scientists. The gold standards for TPE diagnosis are pleural fluid Ziehl–Neelsen staining, Mycobacterium tuberculosis ( Mtb) culture and pleural biopsy. These tools have limitations, including low sensitivity, long turnaround time and invasiveness. The nucleic acid amplification test (NAAT) is a rapid and minimally invasive tool for diagnosing TPE. This review summarizes the diagnostic accuracy of available NAATs for TPE, with a focus on the evidence from systematic reviews and meta-analyses. The NAATs summarized in this review include in-house NAATs, GeneXpert-MTB/RIF, GeneXpert-MTB/RIF Ultra, simultaneous amplification and testing–tuberculosis, FluoroType MTB and loop-mediated isothermal amplification.

Funder

Zhixue Project, Zhiyuan Funding of Inner Mongolia Medical University

Natural and Science Foundation of Inner Mongolia Autonomous Region for Distinguished Young Scholars

Publisher

Future Medicine Ltd

Subject

Microbiology (medical),Microbiology

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fmb-2023-0025

Reference102 articles.

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