Heterologous expression of fungal L-asparaginase: a systematic review-Reference-Cited by-同舟云学术

Heterologous expression of fungal L-asparaginase: a systematic review

Published:2023-10-26 Issue: Volume: Page:
ISSN:1746-0913
Container-title:Future Microbiology
language:en
Short-container-title:Future Microbiology

Author:

Rodrigues Andrade Kellen Cruvinel¹^ORCID,Cordeiro de Abreu Joel Antonio¹^ORCID,Guimarães Marina Borges¹^ORCID,Abrunhosa Letícia Santos¹^ORCID,Leôncio Rodrigues Ana Luisa¹^ORCID,Fonseca-Bazzo Yris Maria¹^ORCID,Silveira Damaris¹^ORCID,Souza Paula Monteiro¹^ORCID,Magalhães Pérola Oliveira¹^ORCID

Affiliation:

1. Laboratory of Natural Products, Health Science School, University of Brasília, Brasília, 70910-900, Brazil

Abstract

Aim: To review the available literature about heterologous expression of fungal L-asparaginase (L-ASNase). Materials & methods: A search was conducted across PubMed, Science Direct, Scopus and Web of Science databases; 4172 citations were identified and seven articles were selected. Results: The results showed that heterologous expression of fungal L-ASNase was performed mostly in bacterial expression systems, except for a study that expressed L-ASNase in a yeast system. Only three publications reported the purification and characterization of the enzyme. Conclusion: The information reported in this systematic review can contribute significantly to the recognition of the importance of biotechnological techniques for L-ASNase production.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação de Apoio à Pesquisa do Distrito Federal

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Publisher

Future Medicine Ltd

Subject

Microbiology (medical),Microbiology

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fmb-2023-0131

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