The first evidence of Seoul hantavirus, hepatitis E virus and rabies virus in Rattus norvegicus in Tehran, Iran

Author:

Azimi Taher1ORCID,Nasrollahian Sina1,Sabour Sahar2,Hadi Nahal1,Azimi Leila3,Rahbarian Nourina4,Karimi Abdollah3,Fallah Fatemeh3,Mansour-Ghanaie Roxana3,Hoseini-Alfatemi Seyedeh Mahsan3,Fahimzad Sayyed Alireza3

Affiliation:

1. Department of Bacteriology & Virology, School of Medicine, Shiraz University of Medical Science, Shiraz, Iran

2. Department of Microbiology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

3. Pediatric Infections Research Center, Research Institute for Children's Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran

4. Department of Parasitology & Mycology, Tehran University of Medical Sciences, P.O. Box 15468-15514, Tehran, Iran

Abstract

Aim: The present study aimed to investigate the frequency of Seoul hantavirus (SEOV), hepatitis E and rabies viruses in Norway rats in Tehran, Iran. Methods: With the aid of a rat ELISA kit, the we identified specific IgG antibodies against the rabies virus. The presence of SEOV and HEV was determined using an SYBR Green-based real-time PCR assay. Results: 1% of the Rattus norvegicus carried the rabies virus. HEV was associated with R. norvegicus obtained from the south of Tehran with the highest frequency (35%). 12% of tests for SEOV were positive. Conclusion: The findings highlight the importance of putting in place rodent control programs and avoiding interaction with rodent populations in urban settings.

Publisher

Future Medicine Ltd

Subject

Virology

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