M2 as a target to combat influenza drug resistance: what does the evidence say?
Author:
Affiliation:
1. Department of Pharmacology & Toxicology, College of Pharmacy & the BIO5 Institute, The University of Arizona, 1657 E. Helen St., Tucson, AZ 85718, USA
Publisher
Future Medicine Ltd
Subject
Virology
Link
https://www.futuremedicine.com/doi/pdf/10.2217/fvl.15.95
Reference23 articles.
1. Influenza virus M2 protein has ion channel activity
2. Structural and dynamic mechanisms for the function and inhibition of the M2 proton channel from influenza A virus
3. Structural basis for proton conduction and inhibition by the influenza M2 protein
4. Molecular dynamics calculations suggest a conduction mechanism for the M2 proton channel from influenza A virus
5. Recent progress in designing inhibitors that target the drug-resistant M2 proton channels from the influenza A viruses
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