Horizontal and vertical self-paced saccades as a diagnostic marker of traumatic brain injury

Author:

Hunfalvay Melissa1,Roberts Claire-Marie2ORCID,Murray Nick3,Tyagi Ankur1,Kelly Hannah4,Bolte Takumi1

Affiliation:

1. RightEye LLC, 7979 Old Georgetown Rd, Suite 801, Bethesda, MD 20814, USA

2. University of the West of England, Department of Psychology, Bristol, Coldharbour Lane, Bristol, BS16 1QY, UK

3. East Carolina University, College of Health & Human Performance, Minges Coliseum 166, Greenville, NC 27858, USA

4. Emory University, Health Sciences, 201 Dowman Dr, Atlanta, GA 30322, USA

Abstract

Aim: Eye tracking tests to measure horizontal and vertical saccades as a proxy for neural deficits associated with traumatic brain injury (TBI) were evaluated in the present study. Methodology: A total of 287 participants reporting either no TBI, mild, moderate or severe TBI participated in a suite of eye tracking tests to measure horizontal and vertical saccadic performance. Results: The horizontal saccades test offered a sensitivity of 0.77 and a specificity of 0.78, similarly the vertical saccades tests offered a sensitivity of 0.64 and a specificity of 0.65. Conclusion: The results indicated that using eye-tracking technology to measure these metrics offers an objective, reliable and quantifiable way of differentiating between individuals with different severities of TBI, and those without a TBI.

Publisher

Future Medicine Ltd

Subject

Clinical Neurology,Neurology

Reference43 articles.

1. Moderate and severe traumatic brain injury in adults

2. Centers for Disease Control and Prevention. Surveillance report of traumatic brain injury-related emergency department visits, hospitalizations, and deaths – United States, 2014 (2019). www.cdc.gov/traumaticbraininjury/pdf/TBI-Surveillance-Report-FINAL_508.pdf

3. Eye movement testing in clinical examination

4. Functional neuroimaging of acute oculomotor deficits in concussed athletes

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