Pregnancy-associated plasma protein-A and the vulnerable plaque-Reference-Cited by-同舟云学术

Pregnancy-associated plasma protein-A and the vulnerable plaque

Published:2014-08 Issue:8 Volume:8 Page:1033-1047
ISSN:1752-0363
Container-title:Biomarkers in Medicine
language:en
Short-container-title:Biomarkers in Medicine

Author:

B Jespersen Camilla H¹,Vestergaard Kirstine R¹,Schou Morten¹,Teisner Børge²,Goetze Jens P³,Iversen Kasper¹

Affiliation:

1. Department of Cardiology, Nordsjællands Hospital Hillerød, Hillerød, Denmark

2. Department of Immunology & Microbiology, University of Southern Denmark, Odense, Denmark

3. Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark

Abstract

For more than a decade, pregnancy-associated plasma protein-A (PAPP-A) has been examined for its relation to acute coronary syndrome (ACS) and the vulnerable plaque. This review summarizes the current knowledge of plasma PAPP-A in relation to nonpregnant individuals focusing on patients with ACS, discusses its use as a possible biomarker for diagnosis and prognosis in ACS, briefly describes the challenges in different assay technologies and describes the effect of heparin administration on PAPP-A concentrations in plasma.

Publisher

Future Medicine Ltd

Subject

Biochemistry (medical),Clinical Biochemistry,Drug Discovery

Link

https://www.futuremedicine.com/doi/pdf/10.2217/bmm.14.53

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