Harnessing the role of epigenetic histone modification in targeting head and neck squamous cell carcinoma-Reference-Cited by-同舟云学术

Harnessing the role of epigenetic histone modification in targeting head and neck squamous cell carcinoma

Published:2022-03 Issue:5 Volume:14 Page:279-293
ISSN:1750-1911
Container-title:Epigenomics
language:en
Short-container-title:Epigenomics

Author:

Suchanti Surabhi¹,Stephen Bjorn J¹,Awasthi Sonali²,Awasthi Sudhir K²,Singh Gyanendra³,Singh Abhijeet¹,Mishra Rajeev²^ORCID

Affiliation:

1. Department of Biosciences, Manipal University Jaipur, Rajasthan, 303007, India

2. Department of Life Sciences, CSJM University, Kanpur, Uttar Pradesh, 208024, India

3. Toxicology Division, ICMR-National Institute of Occupational Health, Ahmedabad, Gujarat, 380016, India

Abstract

Head and neck squamous cell carcinoma (HNSCC) is the sixth most prevalent form of cancer worldwide. Despite advancements made in treatment strategies, the fatality rate of HNSCC is very high. An accumulating body of evidence suggests that epigenetic modification of histones plays an influential role in the development and progression of the disease. In this review we discuss the role of epigenetic modifications in HNSCC and the inter-relationships of human papillomavirus oncoproteins and histone-modifying agents. Further, we explore the possibility of identifying these modifications as biomarkers for their use as drugs in treatment strategies.

Funder

Science and Engineering Research Board

Publisher

Future Medicine Ltd

Subject

Cancer Research,Genetics

Link

https://www.futuremedicine.com/doi/pdf/10.2217/epi-2020-0348

Reference109 articles.

1. Global surveillance of trends in cancer survival 2000–14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries

2. Epidemiologic Trends in Head and Neck Cancer and Aids in Diagnosis

4. Molecular Pathology of Head and Neck Cancer: Implications for Diagnosis, Prognosis, and Treatment

5. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Immunological Signatures for Early Detection of Human Head and Neck Squamous Cell Carcinoma through RNA Transcriptome Analysis of Blood Platelets;Cancers;2024-06-29

2. EPIGENETIC ALTERATIONS DRIVING ONCOGENESIS IN HEAD AND NECK SQUAMOUS CELL CARCINOMA;Experimental Oncology;2023-12-28

3. Implications of oral dysbiosis and HPV infection in head and neck cancer: from molecular and cellular mechanisms to early diagnosis and therapy;Frontiers in Oncology;2023-12-18