Neuroscience of anorexia nervosa: state of the art

Author:

Agrawal Shipra1,Lask Bryan2

Affiliation:

1. Specialist Registrar, Children & Young People’s Centre, 15, Homerton Row, Hackney, London, E9 6ED, UK.

2. Gt Ormond St Hospital for Children, London, Huntercombe Hospitals, UK and, University of Oslo, Norway.

Abstract

Recent research in anorexia nervosa has demonstrated specific and persistent neuropsychological deficits associated with specific, localized and unilateral abnormalities on neuroimaging. These point to an underlying neurobiological substrate, with a disconnection in neural circuitry being implicated. This article summarizes the most relevant studies presented at the 9th London International Conference on Eating Disorders and discusses the treatment implications.

Publisher

Future Medicine Ltd

Subject

Pediatrics,Pediatrics, Perinatology, and Child Health

Reference19 articles.

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3. FramptonI, Hutchinson A: Eating disorders and the brain. In:Eating Disorders in Childhood and Adolescence 3rd Edition.Lask B, Bryant-Waugh R (Eds). Routledge, Oxon, UK125–148 (2007).

4. A systematic review and meta-analysis of set-shifting ability in eating disorders

5. Set shifting in anorexia nervosa: an examination before and after weight gain, in full recovery and relationship to childhood and adult OCPD traits

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