Global trends and challenges in vaccine safety

Abstract

Although vaccines are among the most effective public health interventions, safe delivery of safe vaccines is a priority in order to maintain public confidence and obtain maximum public health benefit. In order to assure that the vaccines we use are safe, adequate vaccine safety assessment is required on a global level. The purpose of this article is to review the current vaccine safety infrastructure, to identify deficits in the current systems and to identify approaches to improving the current infrastructure.