Molecular epidemiology of WU polyomavirus in hospitalized children with acute respiratory tract infection in China-Reference-Cited by-同舟云学术

Molecular epidemiology of WU polyomavirus in hospitalized children with acute respiratory tract infection in China

Published:2017-05 Issue:6 Volume:12 Page:481-489
ISSN:1746-0913
Container-title:Future Microbiology
language:en
Short-container-title:Future Microbiology

Author:

Zhu Teng¹²,Lu Qing-Bin³⁴,Zhang Shu-Yan⁵,Wo Ying²,Zhuang Lu⁵,Zhang Pan-He²,Zhang Xiao-Ai²,Wei Wei⁶,Liu Wei¹²

Affiliation:

1. Graduate School of Anhui Medical University, Hefei 230032, PR China

2. State Key Laboratory of Pathogen & Biosecurity, Beijing Institute of Microbiology & Epidemiology, Beijing 100071, PR China

3. Department of Laboratorial Science and Technology, School of Public Health, Peking University, Beijing 100191, PR China

4. Beijing Key Laboratory of Toxicological Research & Risk Assessment for Food Safety, Beijing 100191, PR China

5. Department of Developmental Biology, Affiliated Bayi Children’s Hospital, PLA Army General Hospital, Beijing 100700, PR China

6. Department of Epidemiology, Tong Zhou Institute of Infectious Disease & Epidemiology, Beijing 101113, PR China

Abstract

Aim: To explore the molecular epidemiology and clinical characteristics of Washington University polyomavirus (WUPyV) infection in pediatric patients with acute respiratory tract infections in China. Materials & methods: A laboratory surveillance was performed to recruit pediatric patients with acute respiratory tract infections. WUPyV was detected using real-time PCR and complete genome was sequenced for randomly selected positive nasopharyngeal aspirate. Results: Altogether 122 (7.5%) of 1617 children found to be infected with WUPyV and 88 (72.1%) were coinfected with other viruses during 2012–2015. The phylogenetic analysis showed that 14 strains from our study formed two new clusters (Id and IIIc) within the Branch I and Branch III, respectively. Conclusion: WUPyV is persistently circulating in China. Surveillance on WUPyV infection in wider areas and long persistence is warranted.

Publisher

Future Medicine Ltd

Subject

Microbiology (medical),Microbiology

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fmb-2016-0144

Reference31 articles.

1. Respiratory Viral Infections in Infants: Causes, Clinical Symptoms, Virology, and Immunology

2. Adenovirus

3. Coxsackievirus A21, Enterovirus 68, and Acute Respiratory Tract Infection, China

4. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

5. Clinical Epidemiology of Bocavirus, Rhinovirus, Two Polyomaviruses and Four Coronaviruses in HIV-Infected and HIV-Uninfected South African Children

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