Aripiprazole for irritability associated with autistic disorder in children and adolescents aged 6–17 years

Author:

Blankenship Kelly12,Erickson Craig A12,Stigler Kimberly A12,Posey David J12,McDougle Christopher J

Affiliation:

1. Christian Sarkine Autism Treatment Center, James Whitcomb Riley Hospital for Children, IN, USA

2. Department of Psychiatry, Indiana University School of Medicine, 702 Barnhill Drive, ROC 4300, Indianapolis, IN 46202, USA

Abstract

Aripiprazole was recently US FDA-approved to treat irritability in children and adolescents with autistic disorder aged 6–17 years. There are currently only two psychotropics approved by the FDA to treat irritability in the autistic population. This drug profile will discuss available studies of aripiprazole in individuals with pervasive developmental disorders, two of which led to its recent FDA approval. We will discuss the efficacy, as well as the safety and tolerability of the drug documented in these studies. In addition, the chemistry, pharmacokinetics, metabolism and mechanism of action of aripiprazole will be reviewed.

Publisher

Future Medicine Ltd

Subject

Pediatrics,Pediatrics, Perinatology and Child Health

Reference26 articles.

1. Diagnostic and Statistical Manual of Mental Disorders. 4th Edition, Text Revision.American Psychiatric Association, Washington, DC, USA69–84 (2000).

2. Risperidone in pervasive developmental disorders

3. HollanderE, Anagnostou E:Clinical Manual for the Treatment of Autism.American Psychiatric Publishing, Inc., Washington, DC, USA99–120 (2007).

4. A Comparison of Haloperidol and Behavior Therapy and Their Interaction in Autistic Children

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