Statin prescribing among hypertensive patients in southwest Nigeria: findings and implications for the future

Author:

Akunne Onyinye Onyeka1,Godman Brian23,Adedapo Aduragbenro Deborah1,Truter Ilse4,Fadare Joseph5

Affiliation:

1. Department of Pharmacology & Therapeutics, University of Ibadan, Nigeria

2. Department of Laboratory Medicine, Division of Clinical Pharmacology, Karolinska Institutet, Karolinska University Hospital Huddinge, SE-141 86, Stockholm, Sweden

3. Strathclyde Institute of Pharmacy & Biomedical Sciences, University of Strathclyde, Glasgow, UK

4. Drug Utilization Research Unit (DURU), Department of Pharmacy, Nelson Mandela Metropolitan University, Port Elizabeth 6031, South Africa

5. Department of Pharmacology, Ekiti State University, Ado-Ekiti, Nigeria

Abstract

Background: Statins reduce cardiovascular risk, especially in patients with hypertension due to their concomitant blood pressure reducing effects. Prescribing generic statins minimizes cost and improves access. Aims: Ascertain current prescribing of statins in Nigeria and potential savings from the increased use of generic statins. Methods: Prospective study involving hypertensive patients attending University College Hospital (Ibadan, Nigeria). Results: In total, 228 hypertensive patients received statins. Atorvastatin was the most prescribed statin, followed by simvastatin, rosuvastatin and finally fluvastatin. Prescribed doses were less than one defined daily dose in the majority, with high use of originators. Average monthly potential savings from increased prescribing of generic statins was US$2635 for atorvastatin and US$10,578 for rosuvastatin. Conclusion: A shift toward increased prescribing generic statins is recommended to minimize costs.

Publisher

Future Medicine Ltd

Subject

Health Policy

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4. The left atrium, atrial fibrillation, and the risk of stroke in hypertensive patients with left ventricular hypertrophy

5. Management of hypertension and dyslipidemia

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