Brain metastases from prostate cancer: an emerging clinical problem with implications for the future therapeutic scenario-Reference-Cited by-同舟云学术

Brain metastases from prostate cancer: an emerging clinical problem with implications for the future therapeutic scenario

Published:2012-12 Issue:12 Volume:8 Page:1585-1595
ISSN:1479-6694
Container-title:Future Oncology
language:en
Short-container-title:Future Oncology

Author:

Caffo Orazio¹,Veccia Antonello²,Russo Lucianna²,Galligioni Enzo²

Affiliation:

1. Medical Oncology Department, Santa Chiara Hospital, Largo Medaglie d’Oro, 38100 Trento, Italy.

2. Medical Oncology Department, Santa Chiara Hospital, Largo Medaglie d’Oro, 38100 Trento, Italy

Abstract

Brain metastases from prostate cancer (PC) seem to be more frequent than in the past, possibly because advances in the treatment of patients with castration-resistant PC have prolonged their survival. Furthermore, docetaxel (the drug of choice for the first-line treatment of castration-resistant PC) cannot cross the blood–brain barrier and control metastatic foci. However, this problem may be overcome by new active drugs such as cabazitaxel.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fon.12.156

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