Bridges play an important role in transportation infrastructure systems. Intelligent and digital management of bridges group is an essential part of the future intelligent transportation infrastructure system. This paper proposes a digital twin system for bridges group in the regional transportation infrastructure network, which is interconnected by measured traffic loads. In physical space, a full-bridge traffic load monitoring system based on information fusion of weigh-in-motion (WIM) and multi-source heterogeneous machine vision is set up on the target bridge to measure traffic loads, also lightweight sensors are employed on the bridges group for structural response information. Furthermore, by establishing mechanical analysis models in the corresponding digital space and using the measured traffic loads as links, the working condition perception and safety warning of all bridges in the regional transportation network is achieved, forming an important support for further intelligent transportation infrastructure system. The proposed digital twin system has been preliminarily implemented in a bridges group around Shanghai, China, demonstrating the feasibility of the technical framework proposed in this paper and the bright prospects.