pH Assist for Highly selective determination of Xipamide by the enhancement of the green emission of Tb3+ optical sensor

Abstract

The highly selective, accurate method for determination of Xipamide was maintained. The method depends on the enhancement of the green emission band of Tb3+ at 545 nm in the presence of different concentration of  Xipamide at pH 4.1 and λex = 320 nm in acetonitrile. The photophysical properties of the green  emissive Tb3+  complex have been elucidated, the terbium was used as optical sensor for the assessment of  Xipamide in the pharmaceutical tablets and body fluids with a concentration range 5.0 ×10−9 – 2.3 ×10−6 mol L−1 of xipamide, correlation coefficient of 0.995 and  detection limit of 8.5 ×10−10 mol L−1.