MODERN RADIOTHERAPY OF THE STOMACH-Reference-Cited by-同舟云学术

MODERN RADIOTHERAPY OF THE STOMACH

Published:2018-11-21 Issue:3 Volume: Page:5-13
ISSN:2079-5343
Container-title:Diagnostic radiology and radiotherapy
language:
Short-container-title:Lučevaâ diagn. ter.

Author:

Konin V. A.¹,Valkov M. Yu.¹,Litinsky S. S.²,Valkova L. E.³,Ruzhnikova A. A.⁴

Affiliation:

1. Northern State Medical University; Arkhangelsk Clinical Oncologic Dispensary

2. National Medical Research Center of Oncology. N.N. Petrova

3. Arkhangelsk Clinical Oncologic Dispensary

4. Northern State Medical University

Abstract

External beam radiation therapy (EBRT) is currently an important component of the treatment of gastric cancer (GC). In accordance with international and domestic recommendations, it can be used in the postoperative period, before the operation and as a sole option, with a curative and palliative purpose, usually in combination with chemotherapy. With the transition of RT to a new technological level, which involves the use of conformal, intensively modulated regimens, and image guidance the revision of indications for and doses of EBRT is required. The article discusses modern approaches to the determination of irradiated volumes in various clinical scenarios of current radiation therapy for GC and strategies aimed at reducing the dose in critical organs at risk and increasing the overall effectiveness of treatment.

Publisher

Baltic Medical Education Center

Subject

General Medicine

Reference35 articles.

1. Macdonald J.S., Smalley S.R., Benedetti J. et al. Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction // N. Engl. J. Med. 2001. Vol. 345. R. 725–730. PMID: 11547741.

2. Nechaeva M.N., Kharitonov Yu.N., Levit M.L., Val'kov M.Yu. Predoperatsionnaya luchevaya terapiya pri rake zheludka: analiz sobstvennykh otdalennykh rezul'tatov i obzor literatury // Vestnik RNTsRR. 2015. T. 15, № 1. Rezhim dostupa: http://vestnik.rncrr.ru/vestnik/v15/papers/nechaeva_v15.htm. [Nechaeva M.N., Haritonov Yu.N., Levit M.L., Val’kov M.Yu. Predoperacionnaya luchevaya terapiya pri rake zheludka: analiz sobstvennyh otdalennyh rezul’tatov i obzor literatury. Vestnik RNCRR, 2015, Vol. 15, No. 1. Rezhim dostupa: http://vestnik.rncrr.ru/vestnik/v15/papers/nechaeva_v15.htm (In Russ.)].

3. Zhang Z.X., Gu X.Z., Yin W.B. et al. Randomized clinical trial on the combination of preoperative irradiation and surgery in the treatment of adenocarcinoma of gastric cardia (AGC)-report on 370 patients // Int. J. Radiat. Oncol. Biol. Phys. 1998. Vol. 42. R. 929–934.

4. Wydmanski J., Suwinski R., Poltorak S. et al. The tolerance and efficacy of preoperative chemoradiotherapy followed by gastrectomy in operable gastric cancer, a phase II study // Radiother. Oncol. 2007. Vol. 82. R. 132–136.

5. Ruzhnikova A.A., Asakhin S.M., Val'kov M.Yu. Khimioluchevoe lechenie mestno-rasprostranennogo neoperabel'nogo raka zheludka: prospektivnyi analiz vyzhivaemosti // Vestnik RNTsRR. 2013. T. 13. URL: http://vestnik.rncrr.ru/vestnik/v13/papers/ruzhnikova1_v13.htm. [Ruzhnikova A.A., Asahin S.M., Val’kov M.Yu. Himioluchevoe lechenie mestno-rasprostranennogo neoperabel’nogo raka zheludka: prospektivnyj analiz vyzhivaemosti. Vestnik RNCRR, 2013, Vol. 13, URL: http://vestnik.rncrr.ru/vestnik/v13/papers/ruzhnikova1_v13.htm (In Russ.)].