Affiliation:
1. Ivanovsky Institute of Virology, N. F. Gamaleya Federal Research Center for Epidemiology and Microbiology
Abstract
The review article is devoted to the state-of-the-art of eradication and functional cure of HIV infection. The issues related to the history of the discovery, characteristics and origin of the main HIV reservoirs, possible approaches to their elimination, exam- ples of the clinical cure of HIV infection and the principal directions of developing tools for targeted destruction of latently infect- ed HIV cell reservoirs are discussed shortly. The circle of methodological approaches for measuring the reservoirs volume is outlined; their advantages and disadvantages are characterized. The procedure for HIV eradication agents’ clinical trials, including the period of analytical interruption of antiretroviral therapy, is described.
Publisher
Baltic Medical Education Center
Subject
Infectious Diseases,Public Health, Environmental and Occupational Health,Immunology
Cited by
2 articles.
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