İskemik İnmenin Etyolojiye Göre Alt Gruplarında Monosit/Hdl-K Oranlarının Karşılaştırılması

Abstract

Abstract Background/Aim:The increase in (MHR) values calculated by the ratio of monocyte to high-density lipoprotein cholesterol (HDL-C) is a parameter that has recently been evaluated as a measure of inflammation and oxidative stress.There are data associated with cardiovascular diseases and carotid artery pathologies.The aim of this study is to seek an answer to the question "Can MHR be a guiding parameter in the differentiation of these pathologies that are blamed in the etiology of ischemic stroke?" Methods:The records of 200 patients with the diagnosis of acute ischemic stroke and whose neurological examination, neuroradiological imaging and monocyte and HDL-C examinations were completed within the first 24 hours after the onset of symptoms were evaluated retrospectively. They were grouped according to the TOAST classification.Measured monocyte values, HDL-C values and MHR values obtained by monocyte/HDL-C ratio were analyzed statistically according to TOAST groups, comorbid diseases and gender. Results:There was a statistically significant increase in MHR in male and in diabetics, without any statistically significant difference between TOAST groups in terms of MHR. Conclusion:MHR is not an appropriate parameter to use in the estimation of these groups, as it does not show any difference between the subgroups of stroke depending on the etiology.