Exploring the Relationship between Cholesterol Synthesis and Vitamin D: Implications and Insight

Abstract

Cholesterol synthesis and vitamin D metabolism are essential processes in the human body, each with distinct roles in maintaining health and homeostasis. While cholesterol synthesis primarily produces cholesterol, a vital component of cell membranes and a precursor for steroid hormones, vitamin D metabolism contributes to calcium and phosphorus homeostasis, skeletal health, and immune function. Recent research has revealed intricate connections between these pathways, highlighting their interplay and mutual regulation. This review explores the interrelationship between cholesterol synthesis and vitamin D metabolism, elucidating the mechanisms underlying their crosstalk and discussing the implications for health and disease.