Severe Ulcerative Colitis Complicated by Malakoplakia Resulting in Proctocolectomy-Reference-Cited by-同舟云学术

Severe Ulcerative Colitis Complicated by Malakoplakia Resulting in Proctocolectomy

Published:2023-01-12 Issue:1 Volume:11 Page:e01257
ISSN:2326-3253
Container-title:ACG Case Reports Journal
language:en
Short-container-title:ACG Case Rep J

Author:

Alphonsus Lotus¹,De Silva Theshani A.¹,Driman David²,Jairath Vipul³⁴⁵

Affiliation:

1. Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada

2. Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, Western University and London Health Sciences Centre, London, Ontario, Canada

3. Division of Gastroenterology, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada

4. Lawson Health Research Institute, Western University, London, Ontario, Canada

5. Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada

Abstract

ABSTRACT We report a 45-year-old man with medically refractory ulcerative colitis with superimposed colonic malakoplakia, presumed related to chronic use of azathioprine and biologics. This is the first reported case of malakoplakia in a patient requiring high doses of combination therapy. Treatment of malakoplakia is not standardized, but can involve systemic antibiotics, or surgical resection, which in this case resulted in proctocolectomy.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Reference3 articles.

1. Case series of malakoplakia involving colon diagnosed in immunocompromised patients;Lim;Gut Liver,2019

2. Malakoplakia of the urinary bladder in a patient with chronic lymphocytic leukemia under ibrutinib therapy: A case report;Sachanas;Anticancer Res,2016

3. Malakoplakia-induced diarrhea in a kidney transplant recipient;Shah;Transplantation,2010

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