Cannabis Improves Clinical Outcomes and Quality of Life in Patients With Chronic Pouchitis-Reference-Cited by-同舟云学术

Cannabis Improves Clinical Outcomes and Quality of Life in Patients With Chronic Pouchitis

Published:2023-08 Issue:8 Volume:10 Page:e01131
ISSN:2326-3253
Container-title:ACG Case Reports Journal
language:en
Short-container-title:ACG Case Rep J

Author:

Naftali Timna¹²^ORCID,Bar-Lev Schleider Lihi³,Kayless Hen¹²,Bromberg Zohar¹,Dotan Iris²⁴,Broide Efrat²⁵

Affiliation:

1. Institute of Gastroenterology and Hepatology, Meir Medical Center, Kfar Saba, Israel

2. Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

3. Soroka University Medical Center and Faculty of Health Sciences, Ben Gurion University of the Negev, Beersheba, Israel

4. Division of Gastroenterology, Rabin Medical Center, Petah Tikva, Israel

5. Jecheskiel Sigi Gonczarowski Pediatric Gastroenterology Unit, Shamir (Assaf Harofeh) Medical Center, Zerifin, Israel

Abstract

ABSTRACT Many patients with ulcerative colitis after ileoanal pouch anastomosis report improvement of pouchitis with the use of cannabis. Nine patients with chronic pouchitis used 1 g/d of cannabis: 7 patients were male with average age 51 ± 16 years. Average partial pouchitis disease activity index were 11 (range 8–17), 6 (range 5–8), and 5 (range 4–8); endoscopic subscores were 7 .3 ± 2.3, 6 ± 1.1, and 4.4 ± 0.9; average bowel movements per day were 14 (range 8–20), 8 (range 2–13), and 10 (range 13–8); and quality of life increased from 72 ± 1 to 90 ± 16 and 97 ± 10 (P = 0.001) before cannabis treatment and after 8–12 and 52 weeks, respectively. No adverse events were reported.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine

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