Cervical Esophageal Adenocarcinoma Arising From Gastric Inlet Patch: A Benign Lesion With Malignant Potential

Author:

Abdul-Baki Kian1,Pavurala Ravi2,Salim Hamza1,Menon Raakhi1,Bigham Lindsay3,Thaker Harshwardhan3,Reep Gabriel2,Parupudi Sreeram2

Affiliation:

1. Internal Medicine, University of Texas Medical Branch, Galveston, TX

2. Department of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston, TX

3. Department of Pathology, University of Texas Medical Branch, Galveston, TX

Abstract

ABSTRACT Proximal esophageal adenocarcinoma is extremely rare. A gastric inlet patch is a lesion of ectopic gastric mucosa usually found in the cervical esophagus and is considered an incidental finding, but there is a risk for malignant transformation. We report the case of a 50-year-old male with gastroesophageal reflux disease with a 6-month history of progressive dysphagia and 20-pound weight loss. Upper endoscopy showed a malignant stricture with adjacent gastric inlet patch. Biopsies obtained from endoscopic ultrasonography showed adenocarcinoma. This case re-emphasizes careful examination of ectopic gastric mucosa and to consider biopsy if there is suspicion for malignant transformation.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine

Reference12 articles.

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4. Prevalence and clinical and endoscopic characteristics of cervical inlet patch (heterotopic gastric mucosa): A systematic review and meta-analysis;Yin;J Clin Gastroenterol.,2022

5. Gastric inlet patches: Symptomatic or silent?;Cock;Curr Opin Otolaryngol Head Neck Surg.,2019

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