Author:
Kuraeva Tamara Leonidovna,Zil'berman Lyubov' Iosifovna,Titovich Elena Vital'evna,Peterkova Valentina Alexandrovna
Abstract
It is universally recognized that autoimmune type 1 diabetes mellitus (DM) is not the only form of this disease in children. Increasingly more children andadolescents present with DM2, MODY, and rarer syndromal forms of DM. The actual prevalence of DM other than DM1 in children and adolescentsis unknown but may be estimated at 10%. Despite rare occurrence of genetic syndromes, they collectively account for almost 5% of DM cases amongchildren. The rapid upgrowth of molecular biology opens up a wide range of possibilities for designating various symptom complexes as nosologically selfconsistentforms. New genetic syndromes associated with DM are annually described. It is important both to adequately identify and treat manifestationsand complications of these syndromes in children and to provide relevant medico-genetic counseling and recommendations to the parents.Key words: non-immune diabetes mellitus, MODY, Wolfram syndrome, neonatal, syndromal forms
Publisher
Endocrinology Research Centre
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine
Cited by
8 articles.
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