Incidence and graveness of helicobacter infection in patients with type 2 diabetes mellitus

Abstract

Aim. To evaluate the frequency of H.pylori infection and efficiency of its eradication in patients with type 2 diabetes mellitus. Materials and methods. The study included 40 patients with DM2 and 38 diabetics with chronic gastritis (CG). H.pylori was detected by urease assayusing 13C-urea. The degree of stomach bacterial contamination was assessed by a semiquantitative histological method. Control groups comprisedpatients with gastric ulcer and CG having undisturbed carbohydrate metabolism. Results. The frequency of H.pylori infection was virtually identical in patients with and without DM2 regardless of gastric problems. However, comparativeanalysis revealed significant correlation between the graveness of infection and duration of DM2 (r=0.84; p