Author:
Tyurenkov Ivan Nikolaevich,Kurkin Denis Vladimirovich,Volotova Elena Vladimirovna,Bakulin Dmitriy Alexandrovich,Lomkina Elena Michailovna
Abstract
In this review we discuss ten promising biological targets of interest for treating type 2 diabetes mellitus, obesity and metabolic syndrome. Namely, we address current experimental and clinical data on several new compounds that affect SGLT2, 11b-HSD1, PTP1B, SCD1, Il-1?. , fructose-1,6-bisphosphatase, glycogen phosphorylase, SIRT1, DGAT-1 and GPR119. The body of data shows potential of these substances to become effective antidiabetic agents.
Publisher
Endocrinology Research Centre
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine
Cited by
5 articles.
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