Adrenal insufficiency (hypocorticism) on the background of adrenalectomy for corticosteroma

Abstract

Adrenal insufficiency (AI) occurs after adrenalectomy for adrenal corticosteroma due to inhibition of the hypothalamicpituitary-adrenal axis and decreased function of the contralateral adrenal gland. Treatment of postoperative AI is based on glucocorticoid replacement therapy and is generally required in all patients with adrenalectomy for Cushing’s syndrome, but dosage and duration of treatment may vary. It is important to educate patients for self-adjustment of substitution therapy dosages and prevention of AI decompensation, it is especially important in this pathology. The article presents a clinical case of a patient with acute adrenal insufficiency that developed against the background of adrenalectomy for corticosteroma of the left adrenal gland.