Potential predictors and the frequency of development of thyroid and gastrointestinal neoplasms in the patients presenting with acromegaly

Abstract

This paper reports the results of research designed to study the possible predictors and the frequency of development of neoplasms in the thyroid gland and the gastrointestinal tract in the patients presenting with acromegaly. Special attention is given to the role of IGF-1 and IRI in the formation of tumours in the aforementioned organs and systems and the dependence of the frequency of their development on the patients’ age and (25)OH)D level. The detailed description of the features of the revealed thyroid and gastrointestinal neoplasms is presented.