Affiliation:
1. Endocrinology Research Center
Abstract
IgG4-related disease is a rare chronic pathology manifested by lymphoplasmacytic infiltration of one or more organs, the formation of storiform fibrosis, tissue edema, and an increase of IgG4 in the blood. This disease was singled out as an independent nosological unit only in 2001. The incidence is less than 1 in 100,000 people per year. Almost any organ can be affected in IgG4-related disease. The association of Riedel's thyroiditis with IgG4 was established in 2010. Riedel's thyroiditis is an extremely rare inflammatory disease of the thyroid gland, which diagnosis is complicated by an atypical course and the absence of characteristic symptoms. Less than 300 clinical cases of the disease have been described in the world, only two from them were in children. This article presents a clinical case of a 6-year-old boy with Riedel's thyroiditis.
Publisher
Endocrinology Research Centre
Reference25 articles.
1. Falhammar H, Juhlin CC, Barner C, Catrina S-B, Karefylakis C, Calissendorff J. Riedel’s thyroiditis: clinical presentation, treatment and outcomes. Endocrine. 2018;60(1):185-192. doi: https://doi.org/10.1007/s12020-018-1526-3
2. Riedel B. Die chronishe, zur Bildung eisenharter Tumoren fuhrende Entzundung der Schildruse. Verh Dtsch Ges Chir, vol. 25, pp. 101–105, 1896
3. Gosi SKY., Nguyen M, Garla VV. Riedel Thyroiditis. 2023 Jul 17. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan
4. Majety P, Hennessey JV. Acute and Subacute, and Riedel’s Thyroiditis. 2022 Jul 25. Endotext [Internet]. South Dartmouth (MA): MDText. com, Inc.; 2000
5. Hamano H, Kawa S, Horiuchi A, et al. High Serum IgG4 Concentrations in Patients with Sclerosing Pancreatitis. N Engl J Med. 2001;344(10):732-738. doi: https://doi.org/10.1056/NEJM200103083441005