Affiliation:
1. Endocrinology Research Centre
Abstract
Diabetes mellitus (DM) type 1 accounts for up to 90% of all cases of diabetes among children, adolescents and young adults (10 % are represented by T2DM, MODY, etc.). DM is characterized not only by glucose metabolism disorder, but also by abnormal protein and lipid metabolism, leading to severe macrovascular complications. A clinical case of diabetes type 1, hyperlipidemia, coronary artery disease (CAD) and chronic heart failure (HF) in a 25-year-old adult has been demonstrated. The medical examination revealed lipid metabolism disorders, multivessel coronary artery disease, which required myocardial revascularization, and severe heart failure with a reduced ejection fraction (HFrEF). The clinical case demonstrates that proper cardiovascular examination should be performed in all patients with diabetes and lipid disorders, regardless of age and type of diabetes. The authors also consider the use of sodium-glucose
Publisher
Endocrinology Research Centre
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine
Reference16 articles.
1. Peterkova VA, Shestakova MV, Bezlepkina OB, et al. Diabetes mellitus type 1 in childhood. Diabetes mellitus. 2020;23(1S):4-40. (In Russ.). doi: https://doi.org/10.14341/DM12504
2. Homma TK, Endo CM, Saruhashi T, et al. Dyslipidemia in young patients with type 1 diabetes mellitus. Arch Endocrinol Metab. 2015;59(3):215-219. doi: https://doi.org/10.1590/2359-3997000000040
3. Mostofizadeh N, Hashemipour M, Roostazadeh M et al. The impact of poor glycemic control on lipid profile variables in children with type 1 diabetes mellitus. J Educ Health Promot. 2019;8:6. doi: https://doi.org/10.4103/jehp.jehp_194_17
4. Swasey KK, Orchard TJ, Costacou T. Trends in cardiovascular risk factor management in type 1 diabetes by sex. J Diabetes Complications. 2018;32(4):411-417. doi: https://doi.org/10.1016/j.jdiacomp.2018.01.003
5. Htay T, Soe K, Lopez-Perez A, et al. Mortality and Cardiovascular Disease in Type 1 and Type 2 Diabetes. Curr Cardiol Rep. 2019;21(6):45. doi: https://doi.org/10.1007/s11886-019-1133-9