Regulation of catalytic activity and nucleolar localization of rat DNA topoisomerase IIα through its C-terminal domain

Author:

Yasuda Kazushi1,Kato Yuri1,Ikeda Shogo1,Kawano Shinji1

Affiliation:

1. Department of Biochemistry, Faculty of Science, Okayama University of Science

Publisher

Genetics Society of Japan

Subject

Genetics,Molecular Biology,General Medicine

Reference40 articles.

1. Adachi, N., Miyaike, M., Kato, S., Kanamaru, R., Koyama, H., and Kikuchi, A. (1997) Cellular distribution of mammalian DNA topoisomerase II is determined by its catalytically dispensable C-terminal domain. Nucleic Acids Res. 25, 3135–3142.

2. Agostinho, M., Rino, J., Braga, J., Ferreira, F., Steffensen, S., and Ferreira, J. (2004) Human topoisomerase IIα: targeting to subchromosomal sites of activity during interphase and mitosis. Mol. Biol. Cell 15, 2388–2400.

3. Austin, C. A., and Fisher, L. M. (1990) Isolation and characterization of a human cDNA clone encoding a novel DNA topoisomerase II homologue from HeLa cells. FEBS Lett. 266, 115–117.

4. Berger, J. M., Gamblin, S. J., Harrison, S. C., and Wang, J. C. (1996) Structure and mechanism of DNA topoisomerase II. Nature 379, 225–232.

5. Capranico, G., Tinelli, S., Austin, C. A., Fisher, M. L., and Zunino, F. (1992) Different patterns of gene expression of topoisomerase II isoforms in differentiated tissues during murine development. Biochim. Biophys. Acta 1132, 43–48.

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