Development of an isogenic human cell trio that models polyglutamine disease
Author:
Affiliation:
1. School of Life Science and Technology, Tokyo Institute of Technology
2. Kanagawa Institute of Industrial Science and Technology
Publisher
Genetics Society of Japan
Subject
Genetics,Molecular Biology,General Medicine
Link
https://www.jstage.jst.go.jp/article/ggs/98/4/98_22-00030/_pdf
Reference30 articles.
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2. An, M. C., O’Brien, R. N., Zhang, N., Patra, B. N., De La Cruz, M., Ray, A., and Ellerby, L. M. (2014) Polyglutamine disease modeling: epitope based screen for homologous recombination using CRISPR/Cas9 system. PLoS Curr. 6, ecurrents.hd.0242d2e7ad72225efa72f6964589369a.
3. Avior, Y., Sagi, I., and Benvenisty, N. (2016) Pluripotent stem cells in disease modelling and drug discovery. Nat. Rev. Mol. Cell Biol. 17, 170–182.
4. Ben Jehuda, R., Shemer, Y., and Binah, O. (2018) Genome editing in induced pluripotent stem cells using CRISPR/Cas9. Stem Cell Rev. Rep. 14, 323–336.
5. Black, M. E., Kokoris, M. S., and Sabo, P. (2001) Herpes simplex virus-1 thymidine kinase mutants created by semi-random sequence mutagenesis improve prodrug-mediated tumor cell killing. Cancer Res. 61, 3022–3030.
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