Potential application of munguba butter in the formulation of nanoemulsified systems

Author:

Raiser A. L.1ORCID,Hoshino T. T.1ORCID,Torres M. P. R.1ORCID,Debiasi B. W.2ORCID,Cotrim A. C. M.1ORCID,Ribeiro E. B.1ORCID,Valladão D. M. S.3ORCID

Affiliation:

1. Universidade Federal do Mato Grosso, Brasil

2. Universidade de São Paulo, Brasil

3. Universidade Federal do Mato Grosso, Brasil; Universidade Federal do Mato Grosso, Brasil

Abstract

Abstract Munguba butter has bioactive compounds such as vitamin E and phytosterols, which has valued its application in the development of new products, with advantages in its use in emulsified formulations. Therefore, the objective was to develop and evaluate the stability of a nanoemulsion containing munguba butter as the oily phase. Munguba butter was extracted by the ultrasound assisted method and its HLB (hydrophilic-lipophilic balance) was determined. Next, formulations varying the concentration of butter from 1-40% were developed and classified into liquid or solid emulsion and phase separation. Liquid emulsions were evaluated for hydrodynamic particle diameter, polydispersity index (PDI), Zeta potential (ζ), rheological characterization, and stability assays. The butter had an HLB of 6.98. The NE 1.0% formulation was selected and demonstrated to be unstable at high temperatures (45 ± 2 °C) and remained stable at room temperature, refrigeration and light radiation for 90 days. Munguba butter, because it has high amounts of saturated fatty acids, hinders its application in the development of new products. However, the success in the development of the NE 1.0% formulation is noteworthy, remaining stable when exposed to refrigeration, room temperature and light radiation.

Publisher

FapUNIFESP (SciELO)

Reference21 articles.

1. Resolução da Diretoria Colegiada – RDC nº 298, de 12 de agosto de 2019. Dispõe sobre a aprovação da Farmacopeia Brasileira, 6ª edição.,2019

2. Resolução RDC nº 481, de 15 de março de 2021. Dispõe sobre os requisitos sanitários para óleos e gorduras vegetais,2021

3. Development and evaluation of emulsifying systems of the material grease from Brazilian flora;DOURADO D.;Journal of Pharmacy & Pharmacognosy Research,2015

4. Microemulsion of Brazil nut oil as a natural product to improve superoxide release in human phagocytes;FIORI K.P.;Quimica Nova,2017

5. Codex Alimetarius,2023

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