Neutropenia: occurrence and management in women with breast cancer receiving chemotherapy

Author:

Nascimento Talita Garcia do1,Andrade Marceila de2,Oliveira Rosemeire Aparecida de3,Almeida Ana Maria de3,Gozzo Thais de Oliveira3

Affiliation:

1. Faculdade Barretos, Brazil

2. Prefeitura Municipal de Ribeirão Preto, Brazil

3. Universidade de São Paulo, Brazil

Abstract

OBJECTIVES: to identify the prevalence, and describe the management of, neutropenia throughout the chemotherapy treatment among women with breast cancer.METHODS: observational study, cycles of chemotherapy. 116 neutropenic events were recorded, and 63.3% of the patients presented neutropenia at some point of their treatment, 46.5% of these presenting grade II. The management used was temporary suspension between the cycles and the mean number of delays was 6 days. The study was prospective and longitudinal, where the evaluation of the hematological toxicities was undertaken at each cycle of chemotherapy, whether neoadjuvant or adjuvant.RESULTS: 79 women were included, who received 572 cycles. However, the reasons for the suspensions were the lack of a space in the chemotherapy center, followed by neutropenia.CONCLUSION: neutropenia is one of the most common and serious adverse events observed during the chemotherapy. Nursing must invest in research regarding this adverse event and in management strategies for organizing the public health system, so as to offer quality care.

Publisher

FapUNIFESP (SciELO)

Subject

General Nursing

Reference22 articles.

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3. The combination of epirubicin plus docetaxel as neoadjuvant chemotherapy in locally advanced breast cancer;Hirano A;Anticancer Res.,2006

4. Risk models for predicting chemotherapy-induced neutropenia;Lyman GH;Oncologist.,2005

5. Neutropenic event risk and impaired chemotherapy delivery in six European audits of breast cancer treatment;Schwenkglenks M;Support Care Cancer.,2006

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