High baseline serum total and LDL cholesterol levels are associated with MDR1 haplotypes in Brazilian hypercholesterolemic individuals of European descent

Author:

Rodrigues A.C.1,Rebecchi I.M.M.1,Bertolami M.C.2,Faludi A.A.2,Hirata M.H.1,Hirata R.D.C.1

Affiliation:

1. Universidade de São Paulo, Brasil

2. Instituto Dante Pazzanese de Cardiologia, Brasil

Publisher

FapUNIFESP (SciELO)

Subject

Cell Biology,General Pharmacology, Toxicology and Pharmaceutics,General Medicine,Immunology,Physiology,Biochemistry,General Neuroscience,Biophysics

Reference40 articles.

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2. Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme-A-reductase inhibitors (statins);Igel M;European Journal of Clinical Pharmacology,2001

3. Lactonization is the critical first step in the disposition of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor atorvastatin;Jacobson W;Drug Metabolism and Disposition,2000

4. Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization;Prueksaritanont T;Drug Metabolism and Disposition,2002

5. Pharmacogenomics of drugs affecting the cardiovascular system;Siest G;Clinical Chemistry and Laboratory Medicine,2003

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