Affiliation:
1. Hospital Alemão Oswaldo Cruz, Brazil
2. São Paulo Federal University
Abstract
PURPOSE: Evaluate and classify skin reactions through the Radiation Therapy Oncology Group (RTOG) criteria and characterize factors that can intervene in these reactions. METHOD: Prospective study, with 86 women submitted to adjuvant breast radiotherapy with a total dose of 5040cGy, in a 6 MeV Linear Accelerator. Personal data were collected and breast size was measured (distance between field separation and breast height). The treated skin area was evaluated weekly. RESULTS: Breast height and treatment technique were significant factors in the univariate analysis for the incidence of degree 3 skin reactions. However, only breast height was a significant factor in the multivariate analysis for the severity of skin reactions. The chances of occurring degree 3 reactions increase 2.61 times for each increase in height unit (cm). These findings allow nurses to plan more adequate and individualized procedures for each patient and contribute to the optimization of treatment.
Reference18 articles.
1. Correction of cancer anemia: Impact on disease course, prognosis and treatment efficacy, particularly for patients undergoing radiotherapy;Henke M;Onkologie,2001
2. Acute toxicity of concurrent adjuvant radiotherapy and chemotherapy (CMF or AC) in breast câncer patients: a prospective, comparative, non-randomised study;Fiets WE;Eur Cancer,2003
3. Factors influencing the severity of radiation skin and oral mucosal reactions: development of a conceptual framework;Porock D;Eur Cancer Care,2002
4. Skin toxicity during breast irradiation: pathophysiology and management;Harper JL;South Med,2004
5. Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC);Cox JD;Int J Radiat Oncol Biol Phys,1995
Cited by
31 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献