A semi-automated microscopic image analysis method for scoring Ki-67 nuclear immunostaining

Author:

Fernezlian S.M.1ORCID,Baldavira C.M.1ORCID,Souza M.L.F. de1ORCID,Farhat C.1ORCID,Vilhena A.F. de2ORCID,Pereira J.C.N.3ORCID,Campos J.R.M. de4ORCID,Takagaki T.1ORCID,Balancin M.L.1ORCID,Ab'Saber A.M.1ORCID,Capelozzi V.L.1ORCID

Affiliation:

1. Universidade de São Paulo, Brasil

2. Instituto do Coração, Brasil

3. Georges Pompidou European Hospital, France; International Perioperative Europrogram, France

4. Instituto do Coração, Brasil; Hospital Israelita Albert Einstein, Brasil

Publisher

FapUNIFESP (SciELO)

Subject

Cell Biology,General Pharmacology, Toxicology and Pharmaceutics,General Medicine,Immunology,Physiology,Biochemistry,General Neuroscience,Biophysics,General Medicine

Reference40 articles.

1. Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67;Gerdes J;Am J Pathol,1991

2. Cell-cycle regulation accounts for variability in Ki-67 expression levels;Sobecki M;Cancer Res,2017

3. Ki-67 antigen in lung neuroendocrine tumors: unraveling a role in clinical practice;Pelosi G;J Thorac Oncol,2014

4. Tumor cell proliferation (Ki-67) expression and its prognostic significance in histological subtypes of lung adenocarcinoma;Li Z;Lung Cancer,2021

5. Ki-67 proliferation index in breast cancer as a function of assessment method: a nordiQC experience;Røge R;Appl Immunohistochem Mol Morphol,2021

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