Radioisotopic perfusional assessment of blood circulation changes in skin under progressive expansion: experimental model with rabbits

Author:

Horibe Edith Kawano1,Horibe Kose2

Affiliation:

1. Federal University of São Paulo

2. of São Paulo University

Abstract

The purpose of this experimental model with rabbits is investigating the variation of blood flow in the expanded skin versus expansion time. New Zealand breed rabbits are used. Two groups are studied: F-1 receiving expanders on the right tight and F-2 receiving expanders bilateraly. Progressively, five expansions are performed. The first radioiosotopic perfusional evaluation is performed just after the surgery and the following evaluation are performed at the second, sixth, thirteenth, twentieth and twenty-seventh post-surgical days. As radiotracer, technetium 99m are used in the chemical form of sodium pertechnetate. Scintillographic images are obtained by CGR scintillation camera. The quantitative analysis is done by calculation of the reperfusion rate.

Publisher

FapUNIFESP (SciELO)

Subject

Surgery

Reference8 articles.

1. Reconstruction of the breast after radical mastectomy using temporary expander;Radovan C;Plast Surg Forum.,1978

2. Histomorphologic evaluation of guinea pig skin and soft tissue after controlled tissue expansion;Austad ED;Plast Reconstr Surg.,1982

3. Animal models of human tissue expansion;Bartell TH;Plast Reconstr Surg.,1989

4. Assessment of regional blood flow by intravenous injection of 99m-technetium-pertechnetate;Lindner P;Eur J Nucl Med.,1980

5. Blood flow visualization with the scintillation camera;Powell MR;J Nucl Med.,1996

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