Formulation and characterization of antibacterial orthodontic adhesive

Author:

Twomley Jefferson1ORCID,Wang Yapin2ORCID,Wen Zezhang2ORCID,Yu Qingzhao2ORCID,Ballard Richard2ORCID,Armbruster Paul2ORCID,Xu Xiaoming2ORCID

Affiliation:

1. , USA

2. Louisiana State University Health-New Orleans, USA

Abstract

ABSTRACT Objective: The objective of this study was to formulate experimental orthodontic bracket adhesives and test their mechanical properties, fluoride release and antibacterial activity. Methods: Four experimental antibacterial orthodontic bracket adhesives were prepared with different compositions of synthesized antibacterial monomers replacing total 5% of dental monomers in the control Transbond XT (3M): 5%C11, 3.5%C11+1.5%C2, 5%C16, and 3.5%C16+1.5%C2. Transbond XT alone was used as control. These groups were used to bond premolar brackets to extracted premolars. Shear bond strength (SBS) was tested using an Instron machine. For antibacterial test, disk specimens (10mm diameter, 1mm thick, n=4) were fabricated and incubated with cultures of cariogenic Streptococcus mutans for 48h, and following gentle sonication, S. mutans biofilms in colony-forming-units (CFU) on the disks were enumerated by plating on agar medium. The data were analyzed using ANOVA and Tukey test (α=0.05). Results: All experimental groups had similar shear bond strength (no significant difference) to the control. All experimental groups showed significant inhibitory effect against S. mutans biofilm formation, when compared to the control, but there was no significant difference between experimental groups. Conclusion: Antibacterial orthodontic adhesive can be fabricated to have similar mechanical properties but better caries-inhibitory effect than current adhesive.

Publisher

FapUNIFESP (SciELO)

Subject

Oral Surgery,Orthodontics

Reference30 articles.

1. Incidence of white spot formation after bonding and banding Am;Gorelick L;J Orthod,1982

2. Transmission, diversity and virulence factors of Streptococcus mutans genotypes;Napimoga MH;J Oral Sci,2005

3. The influence of orthodontic fixed appliances on the oral microbiota: a systematic review;Freitas AO;Dental Press J Orthod,2014

4. Fluorides for the prevention of early tooth decay (demineralised white lesions) during fixed brace treatment;Benson PE;Cochrane Database Syst Rev,2013

5. Long-term in vitro fluoride release and rerelease from orthodontic bonding materials containing fluoride;Cohen WJ;Am J Orthod Dentofacial Orthop,2003

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